BIOSTIMULATORS

What are biostimulators?

Biostimulators are injectable treatments that do not simply “fill” the skin, but instead activate the body’s own renewal mechanisms—primarily the production of collagen, elastin, and extracellular matrix. In simple terms, they do not provide immediate volume, but gradually improve skin quality from the inside out. Dr. Konstantinos Floros, with extensive expertise in injectable treatments, applies personalized protocols that “teach” your body how to stay youthful.

What do biostimulators do to the skin?

They act mainly on fibroblasts by:

 

  • Increasing type I & III collagen.
  • Improving hydration, elasticity, and skin density.
  • Enhancing texture, radiance, and skin resilience.

The result is:

  • Firmer skin.
  • Thicker and more resilient
  • More youthful–looking skin, without an “overfilled” appearance.

What are the main advantages of biostimulators?

Choosing this treatment comes with unique benefits for skin quality:

  • Natural result: There is no risk of an “overfilled” or distorted appearance, as the outcome is based on your body’s own collagen production.
  • Improved firmness: The skin becomes thicker, stronger, and more elastic.
  • Long duration: Results develop gradually and can last up to 24 months.
  • Tightening & radiance: They correct dullness and mild skin laxity on the face, neck, and body.
  • Prevention of aging.

What types of materials do biostimulators include?

  1. PLLA (Poly-L-lactic Acid): A powerful collagen stimulator, with results developing over 2–4 months and lasting up to 24 months. Ideal for:

  • Skin laxity.
  • Volume loss.
  • Face & body.

  1. CaHA (Calcium Hydroxylapatite): Also known as Radiesse. It has a dual action: immediate support and long–term collagen stimulation. Ideal for:

  • Facial contouring.
  • Jawline.
  • Neck & hands.

  1. Hybrid Hyaluronic Acid (Bioremodelling – Profhilo): Not a volumizing filler. It improves hydration, elasticity, and overall skin quality. Ideal for:

  • Face.
  • Neck.
  • Decolletage.

  1. Polynucleotides (PN/PDRN): They have regenerative properties with very natural results and are ideal for:

  • Thin, tired skin.
  • Dark circles.
  • Post-laser/peeling recovery.

  1. Autologous Biostimulators – PRP (Platelet Rich Plasma): Uses the patient’s own blood for bio-regeneration, often combined with other treatments. Enhances:

  • Healing.
  • Skin quality.
  • Radiance.

In which areas are biostimulators most commonly applied?

Although the face is the primary treatment area (cheekbones, jawline contour), biostimulators also show impressive results in “difficult” areas such as the neck, decolletage, and the back of the hands. On the body, they are used to improve skin laxity on the arms, abdomen, and thighs.

How are biostimulators used in practice?

Although the face is the main application area (cheekbones, jawline contour), biostimulators also have remarkable effects on “difficult” areas such as the neck, décolletage, and the back of the hands. On the body, they are used to improve skin laxity on the arms, abdomen, and thighs.

Who are biostimulators suitable for?

Biostimulators are ideal for men and women who:

  • Want to improve skin quality rather than add volume.
  • Have skin laxity, thinning, or dull skin.
  • Seek aging prevention.
  • Prefer natural–looking

How is the procedure performed when using biostimulators?

The treatment is performed in the clinic using a very fine needle or microcannula. A topical anesthetic cream is applied beforehand for maximum comfort. The session lasts approximately 20–30 minutes, and the patient can immediately return to daily activities. Usually, a course of 2–3 sessions is required for optimal results.

When do the results of biostimulators become visible?

It is important to understand that biostimulators require patience. The results are not immediate, as the body needs time to produce new collagen. The first improvements in texture and radiance appear after about 4 weeks, while the final tightening effect develops over 3 to 6 months.

Can biostimulators be combined with other treatments?

Absolutely. Dr. Floros often combines biostimulators with:

  • Botulinum Toxin (muscle relaxation).
  • Fillers (structural support).
  • Laser / RF / Microneedling.

Why trust Dr. Konstantinos Floros for their application?

Injecting biostimulators requires deep knowledge of anatomy and facial dynamics. Dr. Floros selects the appropriate material and the correct injection depth, ensuring that collagen production occurs exactly where support is needed. His goal is always to enhance your natural beauty.

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Dr. Konstantinos Floros was born in Athens, studied Medicine at the University of Thessaloniki, and specialized in Plastic Surgery in the United Kingdom. He has participated in specialized aesthetic surgery seminars in London and New York. In Greece, he practices privately with a focus on aesthetic plastic surgery and modern applications of cosmetic medicine and anti-aging. He has served as a Plastic Surgery registrar at the university hospitals Queen Mary’s University Hospital in London and Addenbrooke’s Hospital in Cambridge.

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